Dextromethorphan (Robitussin DM, and others) interacts with BITTER ORANGEīitter orange might decrease how quickly the liver breaks down dextromethorphan.This can cause serious adverse effects such as heart attack and stroke. Taking these products together can increase blood pressure and cause the heart to beat rapidly. Taking bitter orange along with midazolam might increase the effects and side effects of midazolam.īitter orange is a stimulant. Midazolam (Versed) interacts with BITTER ORANGEīitter orange can decrease how quickly the body breaks down midazolam.Some common MAOIs include phenelzine (Nardil), selegiline (Zelapar), and tranylcypromine (Parnate). Taking bitter orange with these medications might cause serious side effects including very fast heartbeat and very high blood pressure. Some medications used for depression can increase these chemicals. Medications for depression (MAOIs) interacts with BITTER ORANGEīitter orange contains chemicals that stimulate the body.Stop taking bitter orange at least 2 weeks before a scheduled surgery. Surgery: Bitter orange acts like a stimulant, so it might interfere with surgery by increasing heart rate and blood pressure. Avoid using bitter orange, especially with stimulants such as caffeine, if you have an irregular heartbeat. Irregular heartbeat (heart arrhythmia): Taking bitter orange, especially together with caffeine, can increase heart rate in healthy people. Heart disease: Taking bitter orange, especially together with caffeine or other stimulants, might increase the risk of serious side effects in people with a particular heart problem called "long QT interval syndrome". Avoid using it if you have this condition. Glaucoma: Bitter orange might worsen glaucoma. Avoid using bitter orange, especially in combination with stimulants such as caffeine, if you have high blood pressure.
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High blood pressure: Taking bitter orange, especially together with caffeine, might increase blood pressure in healthy people. Headache: Taking bitter orange might trigger headaches, including migraines and cluster headaches. Breast-feeding: There isn't enough reliable information to know if bitter orange is safe to use when breast-feeding. Stay on the safe side and stick to food amounts during pregnancy. But it is possibly unsafe when taken by mouth in medicinal amounts. Pregnancy: Bitter orange is likely safe when eaten in the amounts found in food. When inhaled: Bitter orange essential oil is possibly safe when inhaled as aromatherapy. Wear sunblock outside, especially if you are light-skinned. The oil can cause sensitivity to the sun. When applied to the skin: Bitter orange essential oil is possibly safe. There are also reports that bitter orange can trigger headaches in some people. Bitter orange, taken by itself or with stimulants such as caffeine or caffeine-containing herbs, might increase the risk for high blood pressure, fainting, heart attack, stroke, and other serious side effects. But bitter orange is possibly unsafe when taken in the larger amounts used as medicine.
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When taken by mouth: Bitter orange is likely safe when eaten in the amounts found in food.